Operational Resource Center
Practical guidance, carefully sourced resources, tools, templates, and applied examples for clinical trial intake, prescreening, candidate follow-up, coordinator capacity, and enrollment operations.
Choose a starting point
Start with the question you need to answer, then move into the relevant topic, source, tool, example, or service.
You do not need a new page for every question. Start with the question, then move into the C2R resource that already owns it.
Pathway 01 · Learn
Use the six operational pillars for structured overviews, or browse the article archive for focused explanations of intake, prescreening, candidate follow-up, pre-consent handoff readiness, coordinator capacity, enrollment leakage, referral-to-randomization, and enrollment infrastructure.
Pathway 02 · Review the Evidence
Sourced guides identify what type of material supports a claim and separate that material from Consent2Randomize's operational interpretation. This pathway begins with one carefully sourced guide; it does not mean the complete article archive has already received the same source review.
FDA, the HHS Office for Human Research Protections (OHRP), ClinicalTrials.gov, and other applicable authoritative sources.
Peer-reviewed, academic, or credible institutional research.
Established datasets, surveys, and broader market research.
A provider’s own reported case-study or program result.
C2R calculations, models, interpretations, and operational frameworks.
Verified C2R customer performance data only after it exists.
No verified customer results published yet
35%
Research
46 of 133 cancer patients received a response when Ancora.ai used contact information listed on ClinicalTrials.gov in the Tufts Center for the Study of Drug Development (Tufts CSDD)/Ancora.ai pilot.
Why it matters: Patient interest still needs a clear response and next step.
Cancer-only, 17 countries, pilot data, and not a universal referral-response rate.
≈2×
Provider-Reported Result
IQVIA reported 35.21 patients per site at supported sites versus 16.36 at unsupported sites in one Phase III program. ICON separately reported more than twice the recruitment rate at Accellacare sites in another Phase III program.
Why it matters: These provider-reported programs show strong recruitment results at supported sites. They make the role of dedicated support worth examining, without proving that support alone caused the difference.
Provider-reported and program-specific; not universal, not C2R performance, and not proof of one isolated intervention.
4.17×
Research
A systematic review and meta-analysis found online recruitment yielded 4.17 times more participants per active recruitment day than offline recruitment in the seven-study active-day analysis.
Why it matters: The review found a large difference in one recruitment-speed measure between online and offline approaches. Acquisition is still only one part of enrollment.
High heterogeneity; active recruitment days only; not the total recruitment period; offline conversion was higher in the conversion analysis.
≈$40K/day
Research
Tufts CSDD researchers estimated the mean direct daily operating cost of Phase II and Phase III trials combined at about $40,000.
Why it matters: Later-stage trials are expensive to operate, which helps explain why enrollment timelines matter.
Sponsor-level trial economics, not site revenue and not the guaranteed cost of one enrollment-delay day.
If you want a structured way to review where attention may be useful, begin here. The complete categorized tool collection continues below.
Assessments & Scorecards
Structured assessments that help research sites review operational maturity, surface areas for closer review, and establish a site-defined enrollment-infrastructure baseline.
Calculators & Dashboards
Data-driven tools that model enrollment scenarios, timelines, economics, and operational metrics using site-defined inputs and assumptions.
Templates, Workflows & Playbooks
Structured templates, workflow frameworks, and playbooks that research sites can adapt to their enrollment operations.
Pathway 04 · See It Applied
Illustrative examples of recurring intake, follow-up, capacity, and handoff challenges, with practical ways a research team could respond.
Pathway 05 · Find a Solution
Use hands-on support for execution within an approved workflow, consulting for workflow assessment and design, or an Alignment Call when the right starting point is not yet clear.
